STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_450LPS biosynthesis RfbU related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, sp:LN:YV12_MYCTU AC:Q11152, p()=4E-30, pid=25%. (411 aa)    
Predicted Functional Partners:
MTH_354
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YEII_ECOLI AC:P33020, p()=0.46, pid=15%.
  
 
 0.784
MTH_449
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:PABB_LACLA AC:P27629, p()=0.99, pid=15%.
       0.773
cbiD
Cobalamin biosynthesis protein D; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
  
    0.706
hel308
DNA helicase related protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Helicase with 3'-to 5'- polarity; able to unwind over 100 bp of DNA at 50 degrees Celsius. Unwinds forked DNA, preferentially on lagging strand forks; has weaker activity on Holliday junctions. Displaces the invading strand in DNA D- loops. Unwinds short oligonucleotides from dsDNA with 3'- but not blunt ends or 5'-ssDNA tails in an ATP-dependent manner. ATPase activity is stimulated by ssDNA but not dsDNA, protein binds ssDNA, dsDNA with 5'- or 3'-over [...]
  
  
 0.677
MTH_836
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1773354 LN:SAU81973, p()=6.7E-76, pid=38%; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
  
 0.669
MTH_344
UDP-galactopyranose mutase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, sp:LN:GLF_MYCPN AC:P75499, p()=3.3E-51, pid=32%.
  
  
 0.662
MTH_448
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1698878 LN:MMU73378, p()=0.99, pid=12%.
       0.645
MTH_447
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=5.5E-26, pid=20%.
 
   
 0.639
MTH_807
Thioredoxin; Acts to maintain redox homeostasis; functions as a protein disulfide reductase; Belongs to the glutaredoxin family.
  
  
 0.618
MTH_1634
Transcriptional control factor (enhancer-binding protein); Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:Y104_METJA AC:Q57568, p()=7.5E-132, pid=41%.
   
 
 0.576
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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