STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_453Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64496 AC:B64496, p()=0.00012, pid=23%. (252 aa)    
Predicted Functional Partners:
MTH_454
Methyl coenzyme M reductase system, component A2 homolog; Function Code:12.02 - Cell Processes, Transport of carbohydrates organic acids alcohols and lipids; similar to, pir:LN:D64507 AC:D64507, p()=1.2E-35, pid=50%.
 
 
 0.988
bioY
Conserved protein; Probable biotin transporter; Belongs to the BioY family.
  
 0.978
MTH_133
Cobalt transport ATP-binding protein O; Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity).
 
 
 0.918
ecfA
Cobalt transport ATP-binding protein O; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
 0.917
MTH_1706
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YPA1_LEGPN AC:P26880, p()=0.77, pid=12%.
  
 
 0.880
MTH_1015
Methyl coenzyme M reductase system, component A2; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, gp:GI:g293151, p()=2.7E-278, pid=93%.
  
 
 0.879
MTH_151
Methyl coenzyme M reductase system, component A2 homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:D64507 AC:D64507, p()=2.5E-140, pid=51%.
  
 
 0.879
cbiM
Cobalamin biosynthesis protein M; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
 
 0.875
MTH_1707
Cobalamin biosynthesis protein M; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:H64495 AC:H64495, p()=4.6E-29, pid=31%.
  
 
 0.875
MTH_200
Cobalamin biosynthesis protein M related protein; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:B64436 AC:B64436, p()=3.3E-12, pid=25%.
  
 
 0.875
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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