Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_456Magnesium chelatase subunit; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, gp:GI:g1652115 LN:D90902, p()=5.1E-144, pid=34%. (859 aa)    
Predicted Functional Partners:
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
  
 
 0.932
MTH_455
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e218019:g1154782, p()=0.31, pid=09%.
      0.839
MTH_451
Magnesium chelatase subunit ChlI; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:G64413 AC:G64413, p()=2.6E-99, pid=32%.
 
  
 0.828
MTH_671
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:D64374 AC:D64374, p()=0.089, pid=10%.
 
  
 0.738
MTH_556
Magnesium chelatase subunit ChlI; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:G64413 AC:G64413, p()=1.7E-93, pid=45%.
 
  
 0.734
MTH_555
Magnesium chelatase subunit; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, gp:GI:g1651860 LN:D90900, p()=3.6E-18, pid=29%.
 
  
 0.595
MTH_1514
precorrin-6Y methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64490 AC:A64490, p()=2.7E-31, pid=36%.
  
  
 0.567
MTH_453
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64496 AC:B64496, p()=0.00012, pid=23%.
  
  
 0.494
MTH_457
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=1.5E-16, pid=07%.
  
  
 0.459
MTH_458
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1001841, p()=0.0032, pid=23%.
  
  
 0.459
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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