Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_459Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=2E-28, pid=14%. (495 aa)    
Predicted Functional Partners:
MTH_457
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=1.5E-16, pid=07%.
   
 0.972
MTH_458
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1001841, p()=0.0032, pid=23%.
    
 0.771
MTH_447
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=5.5E-26, pid=20%.
   
 0.757
MTH_440
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=2.1E-26, pid=15%.
   
 0.750
MTH_1764
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=2E-21, pid=12%.
   
 0.710
MTH_548
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652473 LN:D90905, p()=1.2E-23, pid=18%.
 
   
 0.692
MTH_1607
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1653584 LN:D90914, p()=4.2E-25, pid=16%.
   
 0.636
MTH_786
Sensory transduction histidine kinase related protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=1.3E-21, pid=46%.
 
     0.525
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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