STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_460Phosphoenolpyruvate synthase homolog; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, pir:LN:F64367 AC:F64367, p()=3.4E-66, pid=37%. (413 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.690
porC
Pyruvate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:F64333 AC:F64333, p()=3.7E-52, pid=42%.
    
 0.591
ppcA
Unknown; Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. Belongs to the PEPCase type 2 family.
     
 0.583
porB
Pyruvate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:C64333 AC:C64333, p()=4.6E-109, pid=66%.
    
 0.580
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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