STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_465Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1786721 LN:ECAE000157, p()=0.44, pid=20%. (319 aa)    
Predicted Functional Partners:
MTH_466
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g607451 LN:HIV1U05479, p()=0.98, pid=04%.
       0.773
MTH_1149
ABC transporter subunit Ycf16; Function Code:12.02 - Cell Processes, Transport of carbohydrates organic acids alcohols and lipids; similar to, gp:GI:g747641 LN:MTU19364, p()=1.8E-123, pid=94%.
 
     0.520
fen
DNA repair protein Rad2; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathwa [...]
     
 0.517
MTH_463
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:G64496 AC:G64496, p()=0.084, pid=23%.
       0.473
MTH_464
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YD79_METJA AC:Q58774, p()=0.9991, pid=12%.
       0.473
uppP
Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
 
  
 0.445
surE
Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
       0.436
truD
Conserved protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
       0.436
comA
Conserved protein; Catalyzes the addition of sulfite to phosphoenolpyruvate (PEP) to yield (2R)-phospho-3-sulfolactate (PSL).
       0.436
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.436
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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