Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MTH_474Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e284003:g1707687, p()=6.3E-32, pid=52%. (77 aa)    
Predicted Functional Partners:
MTH_475
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:CYAA_BORPE AC:P15318, p()=0.8, pid=23%.
       0.582
MTH_473
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1707057, p()=1.7E-49, pid=38%.
  
    0.575
MTH_476
Pyruvate dehydrogenase / acetolactate synthase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1881244 LN:AB001488, p()=1.8E-84, pid=32%; Belongs to the TPP enzyme family.
  
    0.562
MTH_1826
Unknown (contains ferredoxin domain); Function Code:14.00 - Unknown; similar to, pir:LN:A42960 AC:A42960, p()=0.0045, pid=08%.
   
    0.484
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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