STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_504H(2)-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase homolog (III); Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:A64467 AC:A64467, p()=5.1E-101, pid=55%. (347 aa)    
Predicted Functional Partners:
MTH_503
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64467 AC:C64467, p()=8.2E-23, pid=48%.
  
    0.886
MTH_765
GTP-binding protein Rab related protein; Function Code:13.07 - Other, Unclassified; similar to, pir:LN:B64467 AC:B64467, p()=4.8E-27, pid=41%; To M.jannaschii MJ1339.
  
    0.773
MTH_594
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e198926:g1103582, p()=7.2E-10, pid=12%.
  
    0.709
MTH_1836
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64389 AC:B64389, p()=6.1E-27, pid=47%.
  
    0.682
MTH_1828
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1633646 LN:RRU68757, p()=0.6, pid=10%.
  
    0.570
MTH_595
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64467 AC:C64467, p()=9.9E-11, pid=23%.
  
    0.570
mch
N5,N10-methenyl-tetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
     
 0.537
mtd
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
      
 0.531
mer
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT.
     
  0.499
MTH_505
Potassium channel related protein; Function Code:12.05 - Cell Processes, Transport of cations; similar to, pir:LN:S60172 AC:S60172, p()=2.3E-09, pid=16%.
       0.483
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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