Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_515Unknown; Function Code:14.00 - Unknown; similar to, gp_new:GI:d1020550:g2055230 LN:AB000130, p()=0.25, pid=08%. (181 aa)    
Predicted Functional Partners:
MTH_514
Cobalamin biosynthesis protein N; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:D64413 AC:D64413, p()=1.5E-91, pid=22%.
      0.957
MTH_513
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g181688, p()=0.9993, pid=04%.
      0.849
MTH_1514
precorrin-6Y methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64490 AC:A64490, p()=2.7E-31, pid=36%.
  
  
 0.567
MTH_451
Magnesium chelatase subunit ChlI; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:G64413 AC:G64413, p()=2.6E-99, pid=32%.
  
  
 0.445
MTH_556
Magnesium chelatase subunit ChlI; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:G64413 AC:G64413, p()=1.7E-93, pid=45%.
  
  
 0.445
MTH_1022
Biopolymer transport protein; Function Code:12.01 - Cell Processes, Transport of amino acids--peptides and amines; similar to, gp:GI:g1001752, p()=4.6E-13, pid=19%.
  
  
 0.435
MTH_671
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:D64374 AC:D64374, p()=0.089, pid=10%.
  
  
 0.435
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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