STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity). (169 aa)    
Predicted Functional Partners:
msrB
Transcriptional regulator; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, gp:GI:e266415:g1550715, p()=5.8E-38, pid=49%; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.998
MTH_1095
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653851 LN:D90917, p()=0.000000003, pid=35%.
  
 0.941
MTH_1745
Protein disulphide isomerase; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, gp:GI:g699219 LN:MLU15182, p()=0.000000021, pid=22%.
  
 0.941
MTH_807
Thioredoxin; Acts to maintain redox homeostasis; functions as a protein disulfide reductase; Belongs to the glutaredoxin family.
  
 0.941
MTH_895
Conserved protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
  
 0.941
MTH_1577
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YRUB_CLOPA AC:P23171, p()=0.000041, pid=21%.
  
 
 0.928
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
    
 0.758
sod
Superoxide dismutase (Fe/Mn); Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.718
MTH_708
Thioredoxin reductase; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, gp_new:GI:e313024:g1945648 LN:BSZ94043, p()=3.8E-57, pid=42%.
     
 0.683
MTH_1648
Dihydrolipoamide dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:D64379 AC:D64379, p()=8.1E-48, pid=31%.
  
  
 0.602
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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