Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_5362-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:JC4919, p()=2.7E-67, pid=53%. (512 aa)    
Predicted Functional Partners:
MTH_537
2-oxoacid:ferredoxin oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:JC4920, p()=5E-48, pid=37%.
 0.999
korB
2-oxoglutarate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:A64367 AC:A64367, p()=2.1E-88, pid=54%.
 
 0.996
porB
Pyruvate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:C64333 AC:C64333, p()=4.6E-109, pid=66%.
  
 0.991
porC
Pyruvate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:F64333 AC:F64333, p()=3.7E-52, pid=42%.
  
 0.980
korC
2-oxoglutarate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:H64366 AC:H64366, p()=4.2E-51, pid=54%.
  
 0.972
MTH_1032
Ferredoxin (putative 2-oxoglutarate oxidoreductase, delat subunit); Function Code:2.08 - Energy Metabolism, Electron transport; similar to, sp:LN:FER3_METJA AC:Q57610, p()=1.6E-17, pid=45%.
  
 
 0.963
ilvH
Acetolactate synthase, small subunit; Function Code:1.11 - Carbohydrate Metabolism, Butanoate metabolism; similar to, sp:LN:ILVN_METJA AC:Q57625, p()=1.1E-52, pid=53%; Belongs to the acetolactate synthase small subunit family.
  
 
 0.922
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.920
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.920
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.918
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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