STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_5372-oxoacid:ferredoxin oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:JC4920, p()=5E-48, pid=37%. (288 aa)    
Predicted Functional Partners:
MTH_536
2-oxoacid:ferredoxin oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:JC4919, p()=2.7E-67, pid=53%.
 0.999
korA
2-oxoglutarate oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:E64334 AC:E64334, p()=3.6E-116, pid=57%.
 0.996
korC
2-oxoglutarate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:H64366 AC:H64366, p()=4.2E-51, pid=54%.
 
 0.994
porA
Pyruvate oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:D64333 AC:D64333, p()=2.3E-114, pid=58%.
  
 0.990
porC
Pyruvate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:F64333 AC:F64333, p()=3.7E-52, pid=42%.
  
 0.984
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.935
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.933
MTH_476
Pyruvate dehydrogenase / acetolactate synthase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1881244 LN:AB001488, p()=1.8E-84, pid=32%; Belongs to the TPP enzyme family.
  
 
 0.933
vorB
2-oxoisovalerate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:E64334 AC:E64334, p()=1E-51, pid=34%.
 
 0.932
MTH_1032
Ferredoxin (putative 2-oxoglutarate oxidoreductase, delat subunit); Function Code:2.08 - Energy Metabolism, Electron transport; similar to, sp:LN:FER3_METJA AC:Q57610, p()=1.6E-17, pid=45%.
  
 
 0.931
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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