STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_554Conserved protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (188 aa)    
Predicted Functional Partners:
rpl40e
Ribosomal protein L40; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL40_METJA AC:P54058, p()=5.1E-14, pid=55%; Belongs to the eukaryotic ribosomal protein eL40 family.
  
    0.941
MTH_552
Conserved protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids; Belongs to the GGGP/HepGP synthase family. Group II subfamily.
       0.726
eif6
Conserved protein; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
  
 0.695
MTH_858
GTP-binding protein, GTP1/OBG family; Function Code:13.07 - Other, Unclassified; similar to, pir:LN:G64475 AC:G64475, p()=9.7E-68, pid=40%.
 
  
 0.670
MTH_1006
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64355 AC:C64355, p()=2.5E-37, pid=42%.
 
 
 0.638
MTH_555
Magnesium chelatase subunit; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, gp:GI:g1651860 LN:D90900, p()=3.6E-18, pid=29%.
       0.622
rpl30e
Ribosomal protein L30; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL3E_METJA AC:P54061, p()=7.3E-31, pid=66%; Belongs to the eukaryotic ribosomal protein eL30 family.
  
    0.617
MTH_1425
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase fami [...]
 
    0.610
MTH_1005
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y444_METJA AC:Q57886, p()=3.9E-48, pid=41%.
 
  
 0.608
MTH_1214
pre-mRNA splicing protein PRP31; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, pir:LN:F64386 AC:F64386, p()=6.1E-43, pid=23%.
  
  
 0.594
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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