Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
MTH_560Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64440 AC:F64440, p()=9.1E-56, pid=41%. (277 aa)    
Predicted Functional Partners:
MTH_559
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64442 AC:D64442, p()=1E-31, pid=31%.
       0.817
rpl40e
Ribosomal protein L40; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL40_METJA AC:P54058, p()=5.1E-14, pid=55%; Belongs to the eukaryotic ribosomal protein eL40 family.
 
     0.745
mptD
Conserved protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
 
     0.666
MTH_557
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:Y214_METJA AC:Q57667, p()=0.014, pid=27%.
       0.620
MTH_558
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:CH60_TREPA AC:P23033, p()=0.92, pid=17%.
       0.620
MTH_1665
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64427 AC:E64427, p()=3.6E-38, pid=33%.
  
     0.607
rnz
Conserved protein; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
      
 0.515
MTH_1751
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64368 AC:F64368, p()=3.1E-55, pid=38%.
  
     0.503
MTH_1768
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64505 AC:H64505, p()=1.4E-41, pid=30%.
 
     0.502
tgtA
tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family.
  
     0.486
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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