Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MTH_604Adhesion protein; Function Code:13.08 - Other, Adhesion; similar to, gp:GI:g1652186 LN:D90903, p()=2.7E-47, pid=33%. (295 aa)    
Predicted Functional Partners:
MTH_605
ABC transporter; Function Code:12.02 - Cell Processes, Transport of carbohydrates organic acids alcohols and lipids; similar to, gp:GI:g1652187 LN:D90903, p()=6.6E-53, pid=42%.
 
 
 0.999
MTH_606
Manganese transport system membrane protein; Function Code:12.05 - Cell Processes, Transport of cations; similar to, gp:GI:g1652188 LN:D90903, p()=4.7E-52, pid=39%.
 
 
 0.999
rps14
Ribosomal protein S29 (E.coli); Binds 16S rRNA, required for the assembly of 30S particles.
  
  
 0.751
MTH_473
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1707057, p()=1.7E-49, pid=38%.
    
 0.743
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.661
glmM
Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
     
 0.635
MTH_1074
Putative membrane protein; Function Code:11.01 - Cell envelope, Membrane proteins--porins--and lipoproteins; similar to, sp:LN:YPZ5_METTF AC:P29579, p()=2.9E-37, pid=54%.
      
 0.618
MTH_1825
Function Code:11.03 - Cell envelope, Surface proteins--glycoproteins--and structures; similar to, sp:LN:CSG_METFE AC:P27373, p()=2.1E-10, pid=12%.
      
 0.618
MTH_603
Conserved protein; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.
       0.617
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
     
 0.599
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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