STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_609Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1669357 LN:D88555, p()=9.1E-72, pid=90%; Belongs to the UPF0179 family. (147 aa)    
Predicted Functional Partners:
egsA
Glycerol 1-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1- phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea. Is also able to catalyze the reverse reaction, i.e. the NAD(P)(+)-dependent oxidation of G1P but not of G3P. Is not active toward glycerol, dihydroxyacetone, glyceraldehyde-3-phosphate, glyceraldehyde and glycerol-2-phosphate; Belongs to the glycerol-1-phosphate dehydrogenase family.
 
   
 0.950
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.919
MTH_1665
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64427 AC:E64427, p()=3.6E-38, pid=33%.
  
     0.657
MTH_164
Single-stranded DNA exonuclease RecJ related protein; Function Code:10.11 - Metabolism of Macromolecules, DNA degradation--restriction/modification; similar to, pir:LN:A64422 AC:A64422, p()=4.9E-57, pid=32%.
  
     0.646
mptD
Conserved protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
  
     0.630
MTH_1422
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64403 AC:G64403, p()=4.3E-49, pid=29%.
  
     0.620
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). Can inadvertently accommodate and process cysteine.
       0.601
MTH_1324
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y039_METJA AC:Q60351, p()=4.2E-19, pid=37%.
 
     0.595
MTH_967
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64445 AC:C64445, p()=6.7E-44, pid=34%.
  
     0.594
MTH_1751
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64368 AC:F64368, p()=3.1E-55, pid=38%.
  
     0.583
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.