STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_616Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:LON2_BACSU AC:P42425, p()=0.000000055, pid=16%. (442 aa)    
Predicted Functional Partners:
MTH_1702
Secretory protein kinase; Function Code:13.09 - Other, Conjugation; similar to, pir:LN:E64397 AC:E64397, p()=1.5E-89, pid=39%.
 
     0.612
MTH_980
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64397 AC:C64397, p()=0.000085, pid=10%.
 
     0.585
MTH_1703
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:C64397 AC:C64397, p()=0.018, pid=10%.
 
     0.531
MTH_1837
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:SUCA_YEAST AC:P53598, p()=0.18, pid=11%.
  
     0.511
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.469
MTH_617
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:CY1_RHOSH, p()=0.011, pid=%.
       0.464
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.