Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_641Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y613_METJA AC:Q58030, p()=1.9E-17, pid=35%. (140 aa)    
Predicted Functional Partners:
MTH_552
Conserved protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids; Belongs to the GGGP/HepGP synthase family. Group II subfamily.
       0.714
MTH_1267
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y888_METJA AC:Q58298, p()=2.5E-14, pid=26%.
       0.683
MTH_1868
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64350 AC:D64350, p()=3.4E-40, pid=54%.
       0.666
MTH_1869
Activator of (R)-2-hydroxyglutaryl-CoA; Function Code:3.04 - Lipid Metabolism, Sterol biosynthesis; similar to, sp:LN:Y800_METJA AC:Q58210, p()=4.3E-145, pid=66%.
       0.666
MTH_1180
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y094_METJA AC:Q57559, p()=9.5E-93, pid=53%.
       0.664
MTH_1870
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64400 AC:B64400, p()=4.2E-19, pid=31%.
       0.664
MTH_1865
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64476 AC:C64476, p()=5.7E-79, pid=34%; Belongs to the UPF0288 family.
       0.541
MTH_639
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y206_METJA AC:Q57659, p()=3.3E-26, pid=43%.
       0.521
MTH_640
Unknown; Function Code:14.00 - Unknown.
       0.476
MTH_1866
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64362 AC:B64362, p()=2.9E-20, pid=39%.
       0.457
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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