STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_644Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YE26_METJA AC:Q58821, p()=5.2E-37, pid=31%. (157 aa)    
Predicted Functional Partners:
nifH2
Nitrogenase NifH subunit; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
       0.737
MTH_1648
Dihydrolipoamide dehydrogenase; Function Code:1.01 - Carbohydrate Metabolism, Glycolysis--Gluconeogenesis; similar to, pir:LN:D64379 AC:D64379, p()=8.1E-48, pid=31%.
  
 
 0.722
MTH_1096
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653922 LN:D90917, p()=0.0000055, pid=14%.
   
 
 0.693
MTH_1903
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e284341:g1771850, p()=0.00029, pid=17%.
  
 0.682
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.615
MTH_642
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1652042 LN:D90902, p()=0.47, pid=16%.
       0.574
MTH_1222
Inosine-5'-monophosphate dehydrogenase related protein I; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, pir:LN:H64452 AC:H64452, p()=3.6E-22, pid=26%.
 
    0.520
MTH_645
Collagenase; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, sp:LN:Y090_METJA AC:Q57555, p()=1.3E-88, pid=46%.
       0.498
rpl37e
Ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
     
 0.448
MTH_647
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:S61081 AC:S61081:S60817, p()=0.0098, pid=10%.
       0.426
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.