Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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MTH_649Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g495021, p()=1.5E-09, pid=35%; Belongs to the snRNP Sm proteins family. (81 aa)    
Predicted Functional Partners:
rpl37e
Ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
  
  
 0.980
fusA
Translation elongation factor, EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase [...]
   
 0.939
rpl7ae
Ribosomal protein L7a; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.927
rpoH
DNA-dependent RNA polymerase, subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
 
 0.922
hel308
DNA helicase related protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Helicase with 3'-to 5'- polarity; able to unwind over 100 bp of DNA at 50 degrees Celsius. Unwinds forked DNA, preferentially on lagging strand forks; has weaker activity on Holliday junctions. Displaces the invading strand in DNA D- loops. Unwinds short oligonucleotides from dsDNA with 3'- but not blunt ends or 5'-ssDNA tails in an ATP-dependent manner. ATPase activity is stimulated by ssDNA but not dsDNA, protein binds ssDNA, dsDNA with 5'- or 3'-over [...]
  
 0.921
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.896
eif5a
Translation initiation factor, eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
    0.889
MTH_1338
Peptidyl-prolyl cis-trans isomerase B; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, sp:LN:CYPH_SYNP7 AC:P29820, p()=4.5E-38, pid=57%.
   
 0.878
rps24e
Ribosomal protein S24; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS24_HALMA AC:P19953, p()=0.00000001, pid=21%; Belongs to the eukaryotic ribosomal protein eS24 family.
   
 
 0.868
rpl40e
Ribosomal protein L40; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RL40_METJA AC:P54058, p()=5.1E-14, pid=55%; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 
  0.838
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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