Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_650Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64478 AC:G64478, p()=3.3E-35, pid=44%. (160 aa)    
Predicted Functional Partners:
arfB
Conserved protein; Catalyzes the hydrolysis of the formamide of 2-amino-5- formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-monophosphate (FAPy) to form 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (APy).
       0.903
rps28e
Ribosomal protein S28; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS28_METJA AC:P54065, p()=6.4E-16, pid=43%; Belongs to the eukaryotic ribosomal protein eS28 family.
  
 
 
 0.852
MTH_649
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g495021, p()=1.5E-09, pid=35%; Belongs to the snRNP Sm proteins family.
       0.818
MTH_652
Ribonucleotide reductase, large subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
       0.803
rps4e
Ribosomal protein S4; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS4E_METJA AC:P54039, p()=1.2E-60, pid=52%; Belongs to the eukaryotic ribosomal protein eS4 family.
  
 
 
 0.790
rps3ae
Ribosomal protein S3a; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS3A_METJA AC:P54059, p()=4.7E-36, pid=39%; Belongs to the eukaryotic ribosomal protein eS1 family.
  
 
   0.780
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.777
rpl7ae
Ribosomal protein L7a; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 
   0.763
rps3
Ribosomal protein S3 (E.coli); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
    
 
 0.760
pyrF
Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
     0.753
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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