STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_674Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g886362, p()=0.92, pid=04%. (966 aa)    
Predicted Functional Partners:
MTH_673
Magnesium chelatase subunit; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:D64413 AC:D64413, p()=7.1E-100, pid=17%.
     
0.588
MTH_1448
Signal peptidase; Function Code:12.09 - Cell Processes, Protein and peptide secretion; similar to, sp:LN:SPC3_CANFA AC:P13679, p()=0.000000008, pid=24%.
     
 0.513
thsA
Chaperonin; Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity; Belongs to the TCP-1 chaperonin family.
     
 0.505
MTH_1843
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1667516 LN:SPU76538, p()=0.46, pid=11%.
      
 0.504
MTH_1858
Phage infection protein homolog; Function Code:13.07 - Other, Unclassified; similar to, pir:LN:A48653 AC:A48653, p()=4.2E-41, pid=40%.
      
 0.504
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
     
 0.504
atpC
ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
      
 0.504
mrtG
Methyl coenzyme M reductase II, gamma subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
      
 0.499
MTH_412
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e283907:g1707725, p()=0.000000042, pid=05%.
      
 0.499
MTH_965
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YXEQ_BACSU AC:P54956, p()=1.1E-25, pid=27%.
      
 0.499
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.