STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnp2Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (124 aa)    
Predicted Functional Partners:
rnp4
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
   
 0.999
rnp3
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
  
 0.999
rnp1
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
   
 0.969
rpl7ae
Ribosomal protein L7a; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 0.969
MTH_243
Conserved protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
      
 0.783
MTH_689
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y213_METJA AC:Q57666, p()=0.0000017, pid=26%.
       0.781
MTH_685
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64373 AC:H64373, p()=3.2E-60, pid=50%; Belongs to the SDO1/SBDS family.
  
    0.720
psmA
Proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
    0.705
rrp41
Ribonuclease PH; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails; Belongs to the RNase PH family. Rrp41 subfamily.
  
  
 0.694
rrp4
Conserved protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.
  
  
 0.685
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.