STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_689Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y213_METJA AC:Q57666, p()=0.0000017, pid=26%. (138 aa)    
Predicted Functional Partners:
MTH_685
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64373 AC:H64373, p()=3.2E-60, pid=50%; Belongs to the SDO1/SBDS family.
     
 0.910
rpl15e
Ribosomal protein L15; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:R15E_METJA AC:P54060, p()=8.6E-60, pid=66%; Belongs to the eukaryotic ribosomal protein eL15 family.
       0.887
rrp41
Ribonuclease PH; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails; Belongs to the RNase PH family. Rrp41 subfamily.
     
 0.885
rrp42
Conserved protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site; Belongs to the RNase PH family. Rrp42 subfamily.
     
 0.879
MTH_680
Conserved protein; Probably involved in the biogenesis of the ribosome.
     
 0.876
rnp3
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
 
     0.844
csl4
Conserved protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs.
  
   
 0.820
rnp2
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
       0.781
MTH_1203
Cleavage and polyadenylation specificity factor; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, sp:LN:YC36_METJA AC:Q58633, p()=9.1E-191, pid=53%.
      
 0.707
pfdB
Conserved protein; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
     0.707
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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