STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_692Stomatin-like protein; Function Code:11.01 - Cell envelope, Membrane proteins--porins--and lipoproteins; similar to, gp:GI:e264116:g1524234, p()=1.3E-54, pid=39%. (318 aa)    
Predicted Functional Partners:
MTH_693
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e264115:g1524233, p()=0.0000017, pid=26%.
 
  
 0.950
MTH_1903
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e284341:g1771850, p()=0.00029, pid=17%.
  
 0.802
MTH_1639
Cell division control protein Cdc48; Function Code:12.07 - Cell Processes, Cell division; similar to, pir:LN:C64444 AC:C64444, p()=7.7E-233, pid=83%.
   
 0.664
pan
ATP-dependent 26S protease regulatory subunit 4; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone pro [...]
  
 
 0.653
dnaK
DnaK protein (Hsp70); Acts as a chaperone.
  
 0.649
MTH_1485
Serine/threonine protein kinase related protein; Function Code:10.08 - Metabolism of Macromolecules, Protein translation and modification; similar to, sp:LN:YXAL_BACSU AC:P42111, p()=3.3E-35, pid=93%.
  
 
 0.569
MTH_694
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:A64334 AC:A64334, p()=0.0033, pid=11%.
       0.568
asd
Phosphatidylserine decarboxylase; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
   
 
 0.539
MTH_691
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64392 AC:F64392, p()=1.2E-30, pid=47%.
     
 0.528
rpl13/rps9
Ribosomal protein S16 (E.coli); L13 protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity).
  
 
 0.520
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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