STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_696ABC transporter (glutamine transport ATP-binding protein); Function Code:12.01 - Cell Processes, Transport of amino acids--peptides and amines; similar to, pir:LN:D64399 AC:D64399, p()=1.1E-43, pid=39%. (220 aa)    
Predicted Functional Partners:
MTH_695
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YF07_METJA AC:Q58902, p()=6.9E-18, pid=19%.
 
 0.999
rpl13/rps9
Ribosomal protein S16 (E.coli); L13 protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity).
 
   
 0.852
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
 0.664
MTH_921
Anion transport system permease protein; Function Code:12.04 - Cell Processes, Transport of anions; similar to, sp:LN:MBPY_MARPO AC:P26246, p()=3.7E-20, pid=20%.
 
    0.618
rpl2
Ribosomal protein L8 (E.coli); One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
 
   
 0.613
rps5
Ribosomal protein S2 (E.coli); With S4 and S12 plays an important role in translational accuracy.
 
   
 0.599
MTH_233
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64497 AC:E64497, p()=8.6E-44, pid=36%.
 
 
 0.579
MTH_284
ATP-dependent Clp protease regulatory subunit; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, sp:LN:CLAB_LYCES AC:P31542, p()=2.3E-53, pid=22%.
 
  
 0.574
hisS
histidyl-tRNA synthetase; Function Code:10.07 - Metabolism of Macromolecules, Aminoacyl tRNA synthetases and tRNA modification; similar to, sp:LN:SYH_METJA AC:Q58406, p()=8.8E-90, pid=40%; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
   
 0.569
MTH_708
Thioredoxin reductase; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, gp_new:GI:e313024:g1945648 LN:BSZ94043, p()=3.8E-57, pid=42%.
 
  
 0.558
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.