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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_700Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:S18988 AC:S18988, p()=0.00001, pid=10%. (182 aa)    
Predicted Functional Partners:
MTH_701
acetyl-CoA synthetase related protein; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, pir:LN:I54401 AC:I54401, p()=1.3E-72, pid=34%.
 
 0.989
MTH_702
acetyl-CoA synthetase related protein; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, pir:LN:A61209 AC:A61209, p()=9.9E-43, pid=62%.
 
 
 0.943
vorA
2-oxoisovalerate oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:A64367 AC:A64367, p()=5E-28, pid=16%.
 
  
 0.799
vorB
2-oxoisovalerate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:E64334 AC:E64334, p()=1E-51, pid=34%.
 
  
 0.785
MTH_1604
acetyl-CoA synthetase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, gp:GI:g1001254, p()=2.6E-74, pid=53%.
 
 
 0.784
vorC
2-oxoisovalerate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, sp:LN:FER3_METJA AC:Q57610, p()=0.000015, pid=39%.
  
  
 0.749
gatD
L-asparaginase I; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
  
  
 0.724
gatE
PET112-like protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.688
MTH_699
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:YCX1_CUSRE AC:P32035, p()=0.98, pid=06%.
       0.550
MTH_708
Thioredoxin reductase; Function Code:4.02 - Nucleotide Metabolism, Pyrimidine metabolism; similar to, gp_new:GI:e313024:g1945648 LN:BSZ94043, p()=3.8E-57, pid=42%.
  
  
 0.495
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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