STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_702acetyl-CoA synthetase related protein; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, pir:LN:A61209 AC:A61209, p()=9.9E-43, pid=62%. (124 aa)    
Predicted Functional Partners:
MTH_701
acetyl-CoA synthetase related protein; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, pir:LN:I54401 AC:I54401, p()=1.3E-72, pid=34%.
     0.989
MTH_700
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:S18988 AC:S18988, p()=0.00001, pid=10%.
 
 
 0.943
vorC
2-oxoisovalerate oxidoreductase, gamma subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, sp:LN:FER3_METJA AC:Q57610, p()=0.000015, pid=39%.
 
  
 0.921
MTH_1603
acetyl-CoA synthetase; Function Code:1.08 - Carbohydrate Metabolism, Pyruvate and acetyl-CoA metabolism; similar to, sp:LN:ACSA_METSO AC:P27095, p()=5.4E-122, pid=54%.
 
    0.908
vorB
2-oxoisovalerate oxidoreductase, beta subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:E64334 AC:E64334, p()=1E-51, pid=34%.
  
  
 0.849
vorA
2-oxoisovalerate oxidoreductase, alpha subunit; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:A64367 AC:A64367, p()=5E-28, pid=16%.
  
  
 0.842
gatD
L-asparaginase I; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.780
gatE
PET112-like protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.
       0.780
mdh
Lactate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
  
 
 0.666
MTH_657
long-chain-fatty-acid-CoA ligase; Function Code:3.01 - Lipid Metabolism, Fatty acid biosynthesis; similar to, gp:GI:e276127:g1627854, p()=3.2E-101, pid=37%.
 
 
0.639
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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