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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene co-occurrence
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MTH_735phospho-N-acetylmuramoyl-pentapeptide- transferase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, sp:LN:MRAY_BACSU AC:Q03521, p()=1.4E-11, pid=11%; Belongs to the glycosyltransferase 4 family. MraY subfamily. (351 aa)    
Predicted Functional Partners:
MTH_736
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e304651:g1872144 LN:TT11467, p()=1.5E-09, pid=22%.
 
  
 0.874
uppS
Conserved protein; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.845
MTH_873
UDP-N-acetylmuramyl tripeptide synthetase related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, sp:LN:Y258_METJA AC:Q57706, p()=5.2E-25, pid=22%.
 
 
 0.826
glmM
Phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
  
 0.789
rpl13/rps9
Ribosomal protein S16 (E.coli); L13 protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity).
  
    0.763
MTH_530
UDP-N-acetylmuramyl tripeptide synthetase related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp_new:GI:e316022:g2104320, p()=2.8E-11, pid=21%.
 
   
 0.746
uppP
Bacitracin resistance protein; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).
 
   
 0.731
MTH_532
UDP-N-acetylmuramyl tripeptide synthetase related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1001328, p()=0.00039, pid=08%.
  
     0.688
mobA
Molybdopterin-guanine dinucleotide biosynthesis MobA related protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
     
 0.671
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily.
      
 0.659
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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