Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_763Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64449 AC:E64449, p()=1E-189, pid=59%. (729 aa)    
Predicted Functional Partners:
MTH_971
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1469185 LN:D50921, p()=0.85, pid=15%.
 
     0.791
ribL
Autotrophic growth protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
       0.714
MTH_656
ATP-dependent RNA helicase related protein; Function Code:10.02 - Metabolism of macromolecules, Transcription, mRNA synthesis and modification (includes regulators; similar to, pir:LN:H64474 AC:H64474, p()=1.3E-125, pid=34%.
  
    0.701
MTH_1016
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g385923 LN:S61233, p()=1.1E-50, pid=43%.
  
    0.603
MTH_828
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64422 AC:E64422, p()=1.8E-18, pid=25%.
  
     0.599
rnp3
Conserved protein; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
  
     0.592
MTH_163
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64369 AC:F64369, p()=1.2E-51, pid=40%.
  
     0.589
MTH_762
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:e255896:g1469045, p()=0.4, pid=09%.
       0.548
MTH_1913
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:A64360 AC:A64360, p()=3.2E-44, pid=48%.
  
     0.537
hjc
Conserved protein; A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products. Cleaves both mobile and immobile junctions. Converts a synthetic Hj to nicked duplex products. Binds a variety of branched DNA structures but linear dsDNA poorly; cleaves only 4-way junctions. Confers UV and mitomycin C resistance to E.coli cells lacking the endogenous [...]
  
   
 0.530
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.