STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_772Conserved protein (contains ferredoxin domain); Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1652823 LN:D90908, p()=2.5E-44, pid=30%. (375 aa)    
Predicted Functional Partners:
metE
Cobalamin-independent methionine synthase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity).
       0.647
mch
N5,N10-methenyl-tetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
       0.642
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
       0.642
MTH_776
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64356 AC:E64356, p()=0.0000013, pid=19%.
       0.638
MTH_777
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64356 AC:D64356, p()=6.7E-21, pid=33%.
       0.638
uvrC
Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
       0.593
MTH_990
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1652988 LN:D90910, p()=7.4E-22, pid=21%.
 
     0.574
MTH_1109
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64473 AC:B64473, p()=2.2E-45, pid=27%; Belongs to the LarC family.
 
     0.566
MTH_771
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64434 AC:H64434, p()=3.2E-21, pid=33%; Belongs to the UPF0047 family.
       0.562
MTH_1826
Unknown (contains ferredoxin domain); Function Code:14.00 - Unknown; similar to, pir:LN:A42960 AC:A42960, p()=0.0045, pid=08%.
 
     0.551
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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