STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_776Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:E64356 AC:E64356, p()=0.0000013, pid=19%. (101 aa)    
Predicted Functional Partners:
metE
Cobalamin-independent methionine synthase; Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. Can use methylcobalamin and methylcobinamide as methyl donors, but methylcobalamin is not considered to be the physiological substrate (By similarity).
       0.883
MTH_777
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64356 AC:D64356, p()=6.7E-21, pid=33%.
       0.873
MTH_778
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:E64498 AC:E64498, p()=0.0083, pid=06%.
       0.825
thyA
Thymidylate synthase; May catalyze the biosynthesis of dTMP using an unknown cosubstrate; Belongs to the thymidylate synthase family. Archaeal-type ThyA subfamily.
       0.787
mch
N5,N10-methenyl-tetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
       0.775
MTH_772
Conserved protein (contains ferredoxin domain); Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1652823 LN:D90908, p()=2.5E-44, pid=30%.
       0.638
MTH_779
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YQJY_BACSU AC:P54562, p()=3.2E-14, pid=23%.
       0.488
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Function Code:4.01 - Nucleotide Metabolism, Purine metabolism; similar to, sp:LN:PUR5_METJA AC:Q57656, p()=2.6E-81, pid=47%.
       0.436
MTH_802
Aspartokinase II alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, gp:GI:e255104:g1770047 LN:BSZ75208, p()=1.4E-36, pid=29%; Belongs to the aspartokinase family.
       0.436
MTH_771
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64434 AC:H64434, p()=3.2E-21, pid=33%; Belongs to the UPF0047 family.
       0.417
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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