STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_781Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:A64383 AC:A64383, p()=2.6E-58, pid=36%. (357 aa)    
Predicted Functional Partners:
MTH_782
Hydrogenase expression/formation protein HypB; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:B64355 AC:B64355, p()=6.3E-64, pid=58%.
       0.865
hypA
Hydrogenase expression/formation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
       0.792
MTH_272
Acetyl / acyl transferase related protein; Function Code:3.01 - Lipid metabolism, Fatty acid biosynthesis; similar to, gp:GI:g992972, p()=2E-12, pid=39%.
 
    0.655
MTH_836
UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, gp:GI:g1773354 LN:SAU81973, p()=6.7E-76, pid=38%; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
   
 0.610
MTH_837
UDP-N-acetylglucosamine 2-epimerase; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:G64487 AC:G64487, p()=3.2E-85, pid=38%.
 
    0.556
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
       0.553
MTH_590
N-acetylglucosamine-1-phosphate transferase; Function Code:11.02 - Cell envelope, Surface polysaccharides and lipopolysaccharides; similar to, pir:LN:H64438 AC:H64438, p()=4.4E-40, pid=27%.
 
     0.547
MTH_875
3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein; Function Code:13.07 - Other, Unclassified; similar to, gp:GI:g1001423, p()=5.8E-38, pid=31%.
 
     0.546
MTH_414
Asparagine synthetase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASNH_METJA AC:Q58516, p()=6.4E-73, pid=39%.
 
   
 0.529
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
     0.450
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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