Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_786Sensory transduction histidine kinase related protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=1.3E-21, pid=46%. (413 aa)    
Predicted Functional Partners:
MTH_444
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1001165, p()=1.2E-32, pid=19%.
 
     0.937
MTH_1607
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1653584 LN:D90914, p()=4.2E-25, pid=16%.
   
 0.880
MTH_985
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=3.7E-43, pid=32%.
 
    
0.880
MTH_902
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=1.7E-10, pid=10%.
   
 0.845
MTH_123
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=2.1E-31, pid=21%.
 
     0.821
MTH_901
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=2E-24, pid=18%.
   
 0.728
MTH_446
Sensory transduction regulatory protein; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=8.9E-39, pid=19%.
     0.683
MTH_468
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp:GI:g1652472 LN:D90905, p()=3.6E-26, pid=12%.
 
     0.659
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily.
 
     0.590
MTH_1260
Sensory transduction histidine kinase; Function Code:12.12 - Cell Processes, Broad regulatory functions; similar to, gp_new:GI:e314507:g2072665, p()=0.00021, pid=10%.
 
     0.578
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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