STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_798Bacitracin transport permease related protein; Function Code:12.09 - Cell Processes, Protein and peptide secretion; similar to, sp:LN:Y374_METJA AC:Q57819, p()=1.7E-13, pid=28%. (186 aa)    
Predicted Functional Partners:
MTH_657
long-chain-fatty-acid-CoA ligase; Function Code:3.01 - Lipid Metabolism, Fatty acid biosynthesis; similar to, gp:GI:e276127:g1627854, p()=3.2E-101, pid=37%.
  
 0.956
rpl6
Ribosomal protein L9 (E.coli); This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
 
 
 0.944
atpC
ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.938
atpF
ATP synthase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 
 0.870
tfs
Transcription elongation factor TFIIS; Induces RNA cleavage activity in the RNA polymerase. In its presence, the cleavage activity of the RNA polymerase truncates the RNA back to position +15 in a stepwise manner by releasing mainly dinucleotides from the 3'-end of the nascent RNA. The truncated RNAs are able to continue elongation. Involved in transcriptional proofreading and fidelity. Misincorporation of nucleotides during elongation of transcription leads to arrested elongation complexes which are rescued by TFS-promoted removal of a dinucleotide from the 3'-end. TFS is able to indu [...]
   
 0.866
atpI
ATP synthase, subunit I; Produces ATP from ADP in the presence of a proton gradient across the membrane; Belongs to the V-ATPase 116 kDa subunit family.
   
 
 0.814
asd-2
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
     
 0.797
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
       0.780
rpoK
DNA-dependent RNA polymerase, subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
   
 
 0.774
MTH_1347
Probable ATP-dependent helicase; Function Code:10.09 - Metabolism of macromolecules, DNA replication, modification, repair, and recombination; similar to, pir:LN:F64417 AC:F64417, p()=0.00025, pid=17%.
  
 
 0.762
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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