STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
MTH_802Aspartokinase II alpha subunit; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, gp:GI:e255104:g1770047 LN:BSZ75208, p()=1.4E-36, pid=29%; Belongs to the aspartokinase family. (406 aa)    
Predicted Functional Partners:
asd-2
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
 
 
 0.999
MTH_417
Homoserine dehydrogenase homolog; Function Code:5.02 - L-Amino Acid Metabolism, Glycine--serine and threonine metabolism; similar to, pir:LN:A64500 AC:A64500, p()=2.1E-79, pid=49%.
 
 0.985
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
  
 0.985
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
   
 0.979
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
  
 0.959
MTH_253
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
 
 0.934
MTH_1894
Aspartate aminotransferase homolog; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:AAT_METJA AC:Q60317, p()=6.1E-82, pid=46%.
 
 0.915
MTH_414
Asparagine synthetase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASNH_METJA AC:Q58516, p()=6.4E-73, pid=39%.
  
 
 0.915
argG
Argininosuccinate synthase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:ASSY_METJA AC:Q60174, p()=2.4E-135, pid=62%; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 
 0.905
MTH_1232
Homoserine dehydrogenase; Function Code:5.02 - L-Amino Acid Metabolism, Glycine--serine and threonine metabolism; similar to, sp:LN:DHOM_SYNY3 AC:P52986, p()=8.8E-90, pid=46%.
 
 0.889
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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