STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_806Protease IV; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, sp:LN:Y651_METJA AC:Q58067, p()=2E-35, pid=28%. (287 aa)    
Predicted Functional Partners:
MTH_204
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YGFA_ECOLI AC:P09160, p()=0.00076, pid=12%.
  
  
 0.614
MTH_807
Thioredoxin; Acts to maintain redox homeostasis; functions as a protein disulfide reductase; Belongs to the glutaredoxin family.
     
 0.613
thiL
Thiamine monphosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
 
     0.581
pyrF
Orotidine 5' monophosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
   
 0.555
MTH_1840
Cell division inhibitor; Function Code:12.07 - Cell Processes, Cell division; similar to, sp:LN:Y547_METJA AC:Q57967, p()=9.1E-56, pid=46%.
 
   
 0.555
MTH_1211
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:A64447 AC:A64447, p()=4.5E-31, pid=25%.
 
   
 0.541
MTH_804
Chorismate mutase, subunit A; Function Code:5.11 - Tyrosine metabolism; similar to, pir:LN:G64330 AC:G64330, p()=8.9E-10, pid=32%.
       0.523
MTH_981
Aminopeptidase P; Function Code:10.12 - Degradation of proteins, peptides, and glycopeptides; similar to, pir:LN:F64400 AC:F64400, p()=1.1E-45, pid=35%; Belongs to the peptidase M24B family.
     
 0.513
MTH_550
DNA-dependent DNA polymerase family X; Function Code:10.09 - Metabolism of Macromolecules, DNA replication--modification--repair--and recombination; similar to, gp:GI:e255092:g1770035 LN:BSZ75208, p()=9.1E-56, pid=43%.
 
     0.510
cbiD
Cobalamin biosynthesis protein D; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
     
 0.507
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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