Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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cbiDCobalamin biosynthesis protein D; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (364 aa)    
Predicted Functional Partners:
MTH_1408
Cobalamin biosynthesis protein G; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, sp:LN:CBIG_SALTY AC:Q05631, p()=1.2E-32, pid=29%.
 
 
 0.998
cbiJ
Cobalamin biosynthesis protein J; Catalyzes the reduction of the macrocycle of cobalt- precorrin-6A to cobalt-precorrin-6B.
 
 0.997
cbiC
Precorrin isomerase; Catalyzes the conversion of cobalt-precorrin-8 to cobyrinate. Belongs to the CobH/CbiC family.
  
 0.997
MTH_1348
Precorrin-2 methyltransferase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:C64396 AC:C64396, p()=4.8E-27, pid=32%; Belongs to the precorrin methyltransferase family.
  
 0.991
MTH_1514
precorrin-6Y methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64490 AC:A64490, p()=2.7E-31, pid=36%.
 
  
 0.979
cbiT
precorrin-8W decarboxylase; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
 
  
 0.976
MTH_602
Precorrin-3 methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64497 AC:A64497, p()=3.3E-74, pid=58%.
 
  
 0.973
cbiH
Precorrin-3 methylase; Methyltransferase that likely catalyzes the ring contraction and methylation of C-17 in cobalt-factor III to form cobalt-factor IV. May also convert cobalt-precorrin-3 to cobalt-precorrin-4 (By similarity).
 
  
 0.971
hel308
DNA helicase related protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Helicase with 3'-to 5'- polarity; able to unwind over 100 bp of DNA at 50 degrees Celsius. Unwinds forked DNA, preferentially on lagging strand forks; has weaker activity on Holliday junctions. Displaces the invading strand in DNA D- loops. Unwinds short oligonucleotides from dsDNA with 3'- but not blunt ends or 5'-ssDNA tails in an ATP-dependent manner. ATPase activity is stimulated by ssDNA but not dsDNA, protein binds ssDNA, dsDNA with 5'- or 3'-over [...]
  
    0.867
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity); Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.863
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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