Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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moaCMolybdenum cofactor biosynthesis protein MoaC; Together with MoaA, is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z); Belongs to the MoaC family. (159 aa)    
Predicted Functional Partners:
moaA
Molybdenum cofactor biosynthesis MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
 
 0.999
MTH_149
Molybdenum cofactor biosynthesis protein MoaE; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, gp:GI:g1825695, p()=2.5E-10, pid=28%.
  
 
 0.995
MTH_1861
Molybdenum cofactor biosynthesis MoaB; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, pir:LN:H64320 AC:H64320, p()=5.7E-31, pid=39%.
  
 0.994
MTH_1369
Molybdenum cofactor biosynthesis MoeA; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, pir:LN:B64383 AC:B64383, p()=3E-64, pid=38%.
 
  
 0.927
MTH_62
Molybdenum cofactor biosynthesis A (MoaA) related protein; Function Code:9.11 - Metabolism of Cofactors and Vitamins,Molybdopterin; similar to, pir:LN:F64503 AC:F64503, p()=1.3E-56, pid=44%.
 
  
 0.886
trpC
Indole-3-glycerol phosphate synthase; Function Code:5.14 - L-Amino Acid Metabolism, Phenylalanine--tyrosine and tryptophan biosynthesis; similar to, sp:LN:TRPC_METTH AC:P26939, p()=2.8E-102, pid=64%.
    
 0.830
hel308
DNA helicase related protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. Helicase with 3'-to 5'- polarity; able to unwind over 100 bp of DNA at 50 degrees Celsius. Unwinds forked DNA, preferentially on lagging strand forks; has weaker activity on Holliday junctions. Displaces the invading strand in DNA D- loops. Unwinds short oligonucleotides from dsDNA with 3'- but not blunt ends or 5'-ssDNA tails in an ATP-dependent manner. ATPase activity is stimulated by ssDNA but not dsDNA, protein binds ssDNA, dsDNA with 5'- or 3'-over [...]
       0.772
MTH_1003
Molybdenum cofactor biosynthesis protein MoeA; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, pir:LN:F64410 AC:F64410, p()=1.8E-66, pid=37%.
 
  
 0.758
MTH_811
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64380 AC:F64380, p()=4E-14, pid=21%; Belongs to the UPF0305 family.
       0.758
MTH_1571
Molybdopterin biosynthesis protein MoeB homolog; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, gp:GI:e290745:g1781245, p()=1.6E-22, pid=28%.
 
   
 0.732
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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