STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MTH_830Conserved protein; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P). (329 aa)    
Predicted Functional Partners:
MTH_1632
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64400 AC:G64400, p()=1.2E-21, pid=34%.
     0.924
hacB
3-isopropylmalate dehydratase, LeuD subunit; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B (By similarity); Belon [...]
       0.875
MTH_831
Molybdenum cofactor biosynthesis MoaA homolog; Function Code:9.11 - Metabolism of Cofactors and Vitamins, Molybdopterin; similar to, pir:LN:C64377 AC:C64377, p()=8.1E-135, pid=50%.
       0.792
mch
N5,N10-methenyl-tetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family.
 
   
 0.785
MTH_743
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y227_METJA AC:Q57680, p()=1.7E-45, pid=37%.
 
     0.774
MTH_1741
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y107_METJA AC:Q57571, p()=1.5E-108, pid=44%.
 
     0.773
MTH_1557
Tungsten formylmethanofuran dehydrogenase, subunit A; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:S57456 AC:S57456, p()=0, pid=94%.
 
     0.767
MTH_947
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64396 AC:H64396, p()=6E-36, pid=26%.
 
     0.756
ftr
Formylmethanofuran:tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.730
ehaS
Formylmethanofuran:tetrahydromethanopterin formyltransferase II; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, sp:LN:FTR_METTH AC:P21348, p()=1.6E-44, pid=36%; Belongs to the FTR family.
 
     0.722
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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