Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
MTH_862Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64447 AC:F64447, p()=1.1E-22, pid=34%; To M.jannaschii MJ1183. (153 aa)    
Predicted Functional Partners:
MTH_863
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64481 AC:D64481, p()=2.3E-11, pid=22%; To M.jannaschii MJ1453.
       0.779
MTH_860
Glucosamine--fructose-6-phosphate aminotransferase; Function Code:5.01 - L-Amino Acid Metabolism, Alanine--aspartate and glutamate metabolism; similar to, sp:LN:YHFN_ECOLI AC:P45540, p()=1.7E-29, pid=27%.
       0.567
thiN
Conserved protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
       0.567
ribC
Riboflavin synthase; Function Code:9.02 - Metabolism of Cofactors and Vitamins, Riboflavin metabolism; similar to, gp:GI:e218505:g1419079, p()=3.2E-76, pid=89%.
       0.524
MTH_864
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:S30587 AC:S30587, p()=1.7E-111, pid=88%.
       0.441
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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