STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_877Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:S01072 AC:S01072, p()=0.075, pid=10%. (289 aa)    
Predicted Functional Partners:
MTH_959
ATP synthase, subunit K; Function Code:2.01 - Energy Metabolism, Oxidative phosphorylation; similar to, sp:LN:ATPL_METJA AC:Q57674, p()=4E-19, pid=68%; Belongs to the V-ATPase proteolipid subunit family.
    
  0.627
fni
Conserved protein; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.605
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
     
 0.555
MTH_1098
Bacteriochlorophyll synthase related protein; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
  0.499
MTH_1809
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:S60222 AC:S60222:S60223, p()=0.00031, pid=13%.
     
  0.499
suhB
Extragenic suppressor protein SuhB homolog; Phosphatase with broad specificity; it can dephosphorylate fructose 1,6-bisphosphate, and both D and L isomers of inositol-1- phosphate (I-1-P); Belongs to the inositol monophosphatase superfamily. FBPase class 4 family.
     
 0.469
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
    
 0.459
MTH_875
3-chlorobenzoate-3,4-dioxygenase dyhydrogenase related protein; Function Code:13.07 - Other, Unclassified; similar to, gp:GI:g1001423, p()=5.8E-38, pid=31%.
       0.425
MTH_1807
Phytoene dehydrogenase; Function Code:9.14 - Metabolism of Cofactors and Vitamins, Terpenoid biosynthesis (isomeric hydrocarbon ((C5H8)n); similar to, sp:LN:CRTJ_MYXXA AC:P54979, p()=4.7E-68, pid=31%.
  
  
 0.417
MTH_1808
Phytoene synthase; Function Code:9.14 - Metabolism of Cofactors and Vitamins, Terpenoid biosynthesis (isomeric hydrocarbon ((C5H8)n); similar to, gp:GI:g1928932 LN:MMU92075, p()=1E-24, pid=29%.
  
  
 0.413
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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