Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MTH_882Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp_new:GI:d1020472:g1945085 LN:D88802, p()=0.000005, pid=17%. (261 aa)    
Predicted Functional Partners:
hcp
6Fe-6S prismane-containing protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.780
MTH_1813
Serine protease HtrA; Function Code:10.12 - Metabolism of Macromolecules, Degradation of proteins--peptides--and glycopeptides; similar to, gp:GI:g1652463 LN:D90905, p()=1.9E-48, pid=32%.
   
 
 0.606
MTH_883
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:NU4M_PODAN AC:P15582, p()=0.63, pid=14%.
       0.564
MTH_1096
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653922 LN:D90917, p()=0.0000055, pid=14%.
 
  
 0.552
MTH_884
Teichoic acid biosynthesis related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:F64456 AC:F64456, p()=2.6E-13, pid=15%.
     
 0.550
MTH_881
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:E64469 AC:E64469, p()=0.35, pid=16%.
       0.528
MTH_1267
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y888_METJA AC:Q58298, p()=2.5E-14, pid=26%.
  
  
 0.469
cbiX
Conserved protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel- containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation (Potential). Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni-sirohydrochlorin (Potential).
     
 0.439
MTH_1523
Glucose-1-phosphate adenylyltransferase related protein; Function Code:4.03 - Nucleotide Metabolism, Nucleotide sugars metabolism; similar to, sp:LN:MPG1_YEAST AC:P41940, p()=2E-21, pid=20%.
 
 
 
 0.416
MTH_1013
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:e288126:g1752671, p()=1E-13, pid=25%.
     
 0.400
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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