Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MTH_883Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:NU4M_PODAN AC:P15582, p()=0.63, pid=14%. (328 aa)    
Predicted Functional Partners:
MTH_884
Teichoic acid biosynthesis related protein; Function Code:11.04 - Cell envelope, Murein sacculus and peptidoglycan; similar to, pir:LN:F64456 AC:F64456, p()=2.6E-13, pid=15%.
       0.768
MTH_882
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp_new:GI:d1020472:g1945085 LN:D88802, p()=0.000005, pid=17%.
       0.564
MTH_881
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:E64469 AC:E64469, p()=0.35, pid=16%.
       0.406
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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