Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MTH_886Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:GAR1_SCHPO AC:Q06975, p()=0.0000072, pid=23%; To M.jannaschii MJ0782.1. (92 aa)    
Predicted Functional Partners:
nop10
Unknown; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.
   
 0.992
truB
Centromere/microtubule-binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 0.992
rpl7ae
Ribosomal protein L7a; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
  
 0.983
MTH_1214
pre-mRNA splicing protein PRP31; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, pir:LN:F64386 AC:F64386, p()=6.1E-43, pid=23%.
  
 
 0.964
tfb
Transcription initiation factor TFIIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
  
  
 0.950
MTH_262
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64464 AC:G64464, p()=0.0000046, pid=23%.
   
 
 0.864
MTH_1
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:YL31_HALMA AC:P20571, p()=1.2E-16, pid=27%.
   
 
 0.827
rpl3
Ribosomal protein L3 (E.coli); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.815
rps8e
Ribosomal protein S8; Function Code:10.04 - Metabolism of Macromolecules, Ribosomal proteins; similar to, sp:LN:RS8E_METJA AC:P54055, p()=6.2E-34, pid=51%.
  
  
 0.768
rps4
Ribosomal protein S9 (E.coli); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.763
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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