STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_888Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64380 AC:D64380, p()=6.3E-25, pid=30%. (220 aa)    
Predicted Functional Partners:
MTH_1546
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64455 AC:F64455, p()=2.6E-26, pid=25%.
    
  0.909
MTH_249
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64455 AC:F64455, p()=4E-24, pid=28%; Belongs to the SIS family. PHI subfamily.
    
  0.909
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
   
 
  0.905
fae-hps
D-arabino 3-hexulose 6-phosphate formaldehyde lyase related protein; Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin; In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
 
   
 0.901
MTH_889
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:H64339 AC:H64339, p()=1.1E-29, pid=61%.
       0.794
MTH_887
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:B64499 AC:B64499, p()=1.5E-18, pid=19%.
     
 0.781
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
   
 
 0.769
MTH_203
ATP-dependent RNA helicase, eIF-4A family; Function Code:10.07 - Metabolism of Macromolecules, Aminoacyl tRNA synthetases and tRNA modification; similar to, gp:GI:g1881268 LN:AB001488, p()=1.2E-83, pid=40%; Belongs to the DEAD box helicase family.
   
 
 0.769
MTH_1747
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y7SR_METFE AC:P21336, p()=9.9E-43, pid=36%.
 
   
 0.764
MTH_890
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:F64502 AC:F64502, p()=4.5E-15, pid=24%.
 
     0.593
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.