STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_909Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:ID1_MOUSE AC:P20067, p()=0.012, pid=16%. (182 aa)    
Predicted Functional Partners:
thiI
Conserved protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
     
 0.849
trm1
N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
    
 
 0.786
truB
Centromere/microtubule-binding protein; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 
 0.770
MTH_1016
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g385923 LN:S61233, p()=1.1E-50, pid=43%.
  
 
 0.740
truD
Conserved protein; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
   
 
 0.702
truA
Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
   
 
 0.648
MTH_908
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1787258 LN:ECAE000204, p()=0.993, pid=12%.
       0.566
MTH_907
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, gp:GI:g1653116 LN:D90911, p()=4.7E-18, pid=26%.
       0.555
MTH_910
Unknown; Function Code:14.00 - Unknown; similar to, sp:LN:GUN_CLOAB AC:P15704, p()=0.092, pid=11%.
       0.494
MTH_1692
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, sp:LN:Y062_METJA AC:Q60369, p()=1E-24, pid=30%.
       0.436
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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