STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tfxConserved protein; Transcriptional activator of the fmdECB operon. (122 aa)    
Predicted Functional Partners:
MTH_1557
Tungsten formylmethanofuran dehydrogenase, subunit A; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:S57456 AC:S57456, p()=0, pid=94%.
      
 0.910
MTH_917
Molybdenum formylmethanofuran dehydrogenase, subunit E; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, gp:GI:e244926:g1702945, p()=1.1E-89, pid=93%.
       0.563
MTH_915
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g148160, p()=0.67, pid=09%.
       0.558
mfnA
Glutamate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
      
 0.527
mptA
Conserved protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
      
 0.527
fmdC
Molybdenum formylmethanofuran dehydrogenase, subunit C; Catalyzes the reversible oxidation of CO(2) and methanofuran (MFR) to N-formylmethanofuran (CHO-MFR). Can only oxidize formylmethanofuran. This enzyme is oxygen-labile. In the N-terminal section; belongs to the FwdC/FmdC family.
       0.524
MTH_919
Molybdenum formylmethanofuran dehydrogenase, subunit B; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, gp:GI:e244928:g1702947, p()=7.4E-228, pid=94%.
       0.524
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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