STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_928Cobalamin biosynthesis protein N; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:D64413 AC:D64413, p()=4.4E-113, pid=19%. (1668 aa)    
Predicted Functional Partners:
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
  
 
 0.936
MTH_671
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:D64374 AC:D64374, p()=0.089, pid=10%.
 
  
 0.822
MTH_451
Magnesium chelatase subunit ChlI; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:G64413 AC:G64413, p()=2.6E-99, pid=32%.
 
  
 0.590
MTH_556
Magnesium chelatase subunit ChlI; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:G64413 AC:G64413, p()=1.7E-93, pid=45%.
 
  
 0.573
MTH_1514
precorrin-6Y methylase; Function Code:9.10 - Metabolism of Cofactors and Vitamins, Porphyrin and chlorophyll metabolism; similar to, pir:LN:A64490 AC:A64490, p()=2.7E-31, pid=36%.
  
  
 0.552
MTH_926
Tungsten formylmethanofuran dehydrogenase, subunit F homolog; Function Code:2.02 - Energy Metabolism, Methane metabolism; similar to, pir:LN:S57453 AC:S57453, p()=3.8E-66, pid=41%.
       0.486
MTH_927
Ferredoxin; Function Code:2.08 - Energy Metabolism, Electron transport; similar to, pir:LN:H64377 AC:H64377, p()=0.0000011, pid=24%.
       0.486
MTH_925
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:D64362 AC:D64362, p()=0.000000018, pid=17%.
  
    0.464
MTH_1022
Biopolymer transport protein; Function Code:12.01 - Cell Processes, Transport of amino acids--peptides and amines; similar to, gp:GI:g1001752, p()=4.6E-13, pid=19%.
  
  
 0.451
MTH_924
Molybdate-binding periplasmic protein; Function Code:12.04 - Cell Processes, Transport of anions; similar to, pir:LN:B64127 AC:B64127, p()=2.5E-30, pid=28%.
       0.439
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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