STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MTH_949Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:G64452 AC:G64452, p()=4.5E-15, pid=35%; Belongs to the UPF0216 family. (135 aa)    
Predicted Functional Partners:
MTH_950
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1470309 LN:S81916, p()=0.77, pid=08%.
       0.570
MTH_951
Unknown; Function Code:14.00 - Unknown; similar to, gp:GI:g1890066 LN:D85133, p()=0.034, pid=25%.
       0.563
trm1
N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
       0.436
MTH_1214
pre-mRNA splicing protein PRP31; Function Code:10.02 - Metabolism of Macromolecules, Transcription--mRNA synthesis and modification (includes regulators); similar to, pir:LN:F64386 AC:F64386, p()=6.1E-43, pid=23%.
       0.436
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.436
glnA
Glutamine synthetase; Probably involved in nitrogen metabolism via ammonium assimilation. Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
       0.436
atpD
ATP synthase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.436
MTH_967
Conserved protein; Function Code:14.01 - Unknown, Conserved protein; similar to, pir:LN:C64445 AC:C64445, p()=6.7E-44, pid=34%.
       0.436
MTH_948
Unknown; Function Code:14.00 - Unknown; similar to, pir:LN:S58649, p()=0.023, pid=%.
       0.417
Your Current Organism:
Methanothermobacter thermautotrophicus
NCBI taxonomy Id: 187420
Other names: M. thermautotrophicus str. Delta H, Methanobacterium thermoautotrophicum str. Delta H, Methanobacterium thermoautotrophicum str. deltaH, Methanothermobacter thermautotrophicus str. Delta H, Methanothermobacter thermautotrophicus str. deltaH
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